ABSTRACT

There has been a remarkable growth of research and applications in the field of nanoscience and nanotechnology. The plant mediated nanomaterial has drawn more attention due to its vast application in various fields because of their physico-chemical properties and also for its simple, cost-effective, eco-friendly and relatively reproducible approach. A considerable research interest in the area of nanotechnology has been witnessed using chitosan nanoparticles as they have emerged as one of the most exciting tools due to their increased surface-volume ratio and are of great interest for nanomedicine, biomedical engineering and development of new therapeutic drug release systems with improved bioavailability, increased specificity and sensitivity, and reduced pharmacological toxicity. The nanopolymer was synthesised using ionic gelation technique and was characterized using UV spectrophotometer and FTIR. The optical density at of the broad peak of Chitosan-jasmine nanopolymer was found at 3.5242. The FTIR results recorded the absorption peaks at 2112 cm-1, 1636 cm-1 and 3327 cm-1 which represented the C-H stretch, C=C stretch and O-H bond stretching respectively. Thus, there was a stretching from higher wavelength region to lower wavelength region demonstrating the interaction of tripolyphosphate with chitosan and biomolecules by reduced hydrogen bonding. The present study was designed to determine the cytoprotective and mosquito breeding repellency of Chitosan-jasmine nanopolymer. Altogether, the results of our study lend pharmacological credence to the bio-medical applications, ethno medical use of this plant in traditional system of medicine and as a promising mosquito breeding repellent in the near future. The present research aimed at synthesizing and characterizing a novel chitosan linked plant nanoparticle for nanomedicine, biomedical engineering, industrial and pharmaceutical applications using potent plant source. Keywords: Chitosan nanopolymer, Jasminum sambac, FTIR, Cytoprotection, Mosquito breeding repellence
Publication date: 01/09/2020

https://ijbpas.com/pdf/2020/September/MS_IJBPAS_2020_5182.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.9.5182