ABSTRACT

There are various reasons that have been identified for the infertility in females and one of them is oxidative stress. Oxidative stress (OS) results when the body is not able to neutralize the generation of free radicals or reactive oxygen species (ROS) like hydroxyl radicals and thus an imbalance is generated between pro-oxidants and anti-oxidants. In the ovary, there is a complex relation between ROS and antioxidants. The environment required in vivo for fertilization and embryo development is of low oxygen tension. A fine balance between pro oxidants and anti-oxidants is required for smooth functioning of female reproductive tract. There are various factors which lead to production of oxidative stress in turn causing infertility. The increased oxidative stress can be detected using various biomarkers which are specific to female reproductive tract. The supplementation of antioxidants can help curb the problem of infertility. This study is focused on the causes, testing and treatment of oxidative stress in females which causes infertility. Keywords: Oxidative stress, infertility, antioxidants, ROS
Publication date: 01/07/2020

https://ijbpas.com/pdf/2020/July/MS_IJBPAS_2020_5186.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.7.5186