ABSTRACT

The stability of the complex formed between the Midrodrine Hydrochloride and Metal ions Ag (?), Pd (??), and Cd (??) are evaluated. That are investigated and monitored by the UV Spectrophotometric method. Midrodrine hydrochloride react with Ag(?), Pd(??) & Cd(??) in aqueous buffer solution where by a coloured complex are formed which absorb maximally at 300 nm .The data show that stoichiometric ratio of drug with metal ions 1:1 ratio. The stability constant of complex were calculated to be Ag(?)-midrodrine -5.72 , Pd(??)- midrodrine -7.17 & Cd(??) – midrodrine - 2.24 by jobs continuous variation method. Keywords: Complexation, Stability Constant, Midrodrine Hydrochloride, Spectrophotometer
Publication date: 01/07/2020

https://ijbpas.com/pdf/2020/July/MS_IJBPAS_2020_5100.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.7.5100