FORMULATION OF CLEOME GYNANDRA MICROSPHERES AND EVALUATION OF ANTIMICROBIAL ACTIVITY Authors: Sriram K* and Kalaichelvan VK
ABSTRACT
Objective: The main aim of study was to compare antimicrobial activity of extracts of
Cleome gynandra and it’s Egg Albumin Loaded microsphere against pathogenic strains.
Methods: Collection of plant. Preparation of leaf extract from Cleome gynandra using water.
Preparation of Egg Albumin loaded microsphere of extract of Cleome gynandra by solvent
evaporation technique. Comparison of antimicrobial activity of leaf extracts of Cleome
gynandra and it’s Egg Albumin Loaded microsphere by paper disc diffusion method.
Results: The leaf extract of Cleome gynandra and its egg albumin loaded microsphere
showed good antimicrobial activity against all the tested microorganisms. Conclusion: On
comparing to fresh leave extract, microsphere had shown good antimicrobial activity against
bacteria and fungi. This is may be due to the egg albumin loaded with extract showed greater
release characteristics.
Keywords: Antifungal, Antibacterial, solvent evaporation, Paper disc diffusion Publication date: 01/06/2020 https://ijbpas.com/pdf/2020/June/MS_IJBPAS_2020_5074.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2020/9.6.5074