Vitiligo is a common depigmenting skin disorder, characterized by acquired, idiopathic,
progressive, circumscribed hypomelanosis of the skin and hair, with total absence of
melanocytes microscopically. It occurs worldwide, with an incidence rate of between 0.1%
and 2%. Vitiligo is an important skin disease having a major impact on the quality of life of
the patient suffering from it. The causes of this condition are uncertain but seem to be
dependent on the interaction of genetic, immunological and neurological factors. Vitiligo
coexists with other autoimmune disorders, Sutton or halo nevus, and malignant melanoma.
The substantial disfigurement associated with vitiligo can cause serious emotional stress for
the patient, which necessitates treatment. Vitiligo is associated with numerous autoimmune,
systemic and dermatological diseases such as thyroid disease, alopecia areata, diabetes
mellitus, pernicious anemia, systemic lupus erythematosus, rheumatoid arthritis, Addison’s
disease, inflammatory bowel disease, dermatomyositis, scleroderma, ocular and audiological
abnormalities, psoriasis, and atopic dermatitis. It is essential to increase awareness of these
comorbidities in order to improve the disease burden and quality of life of patients with
vitiligo. In this review paper, we reviewed correlation of vitiligo with these diseases.
Keywords: Vitiligo, Comorbid autoimmune, systemic and dermatological diseases
Publication date: 01/06/2020
https://ijbpas.com/pdf/2020/June/MS_IJBPAS_2020_5063.pdf
Download PDF
https://doi.org/10.31032/IJBPAS/2020/9.6.5063
