ABSTRACT

Balochistan is the largest province of the country and native home of many medicinal plants. Cocculus pendulus (Family: Menispermaceae) is a medicinal plant used in the crude form by the local people for digestive,pain reliving and depressive disorders. Current study was carried out to ethanolic extract of whole plant to determine phytochemical tests, acute toxicity, analgesic activity, forced swimming test and neuropharmacological activities. Ethanolic extract of C. pendulus showed presence of saponins, tannins and flavonoids in phytochemical tests, Inanalgesic activity significant (p<0.05) results in writhing test, tail immersion test, formalin test were observed. Ethanolic extract of C. pendulus also showed significant (p<0.05) CNS depressant results in force swimming test and neuropharmacological activities. Keywords: Analgesic, JhalMagsi, Cocculuspendulus
Publication date: 01/04/2020

https://ijbpas.com/pdf/2020/April/MS_IJBPAS_2019_4848.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2020/9.4.4058