ABSTRACT

Vitamin A is an essential lipophilic biomolecule for many vital metabolic functions such as vision, placental and embryonic development, reproduction, growth, and has a regulatory role in the immune system. Vitamin A cannot be synthesized in the body, so its prime source is dietary products. Moreover, it has a confirmed role as an antioxidant against oxidative stress due to the excessive presence of free radicals as a result of multiple metabolic processes. However, hypervitaminosis A and toxicity may occur as a consequence of ingesting large amounts of vitamin A. So, proper intake of vitamin A, absorption, metabolismin the liver, storage and then targeting the peripheral tissues are all crucial for the proper functioning of the human system.The present review paper is carried out to explain the different aspects which are related to vitamin A metabolism, storage, and release. Keywords: Vitamin A, Retinol binding proteins, Retinoid, Chylomicrons, Hepatic stellate cells
Publication date: 01/04/2020

https://ijbpas.com/pdf/2020/April/MS_IJBPAS_2020_5053.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.4.5053