ASSOCIATION OF HORMONAL CHANGES AND ULTRASOUND FINDINGS IN POLYCYSTIC OVARY SYNDROME IN THE SUBSET OF ALDOLESCENT POPULATION Authors: Fatima M , AMJAD S, AHMED ST, ALI HS, ALI A AND SHAHID MA
ABSTRACT
Aim: To determine the association of ultrasound findings with follicle-stimulating hormone (FSH),
Luteinizing hormone (LH) and free testosterone in adolescents with the polycystic ovarian syndrome
(PCOS).
Study Design: Cross-sectional study.
Place and Duration of Study: the study was conducted at Gynecology OPD of Ziauddin hospital
kiamari, Karachi, from June 2019 to December 2019.
Methodology: Total 44 adolescents (16-22years) with PCOS diagnosed according to Rotterdam
ESHRE/ASRM Consensus criteria 2003 were enrolled in the study. Non-probability consecutive
sampling technique was used. After taking informed consent, participants were evaluated through
clinical interviews, questionnaire, and anthropometric measurements. The participants underwent the
following assessments i.e. transabdominal ultrasonography, hormonal tests (free testosterone, folliclestimulating
hormone, luteinizing hormone), and metabolic tests (including fasting blood
sugar).Participants were divided into two groups based on ultrasound findings. Those with normal
ultrasound were gathered as Group - I and others who had polycystic ovarian morphology (PCOM)
were categorized as Group - II. Results: In our results, most of the adolescents had polycystic ovarian morphology 77.7 % and 23.3%
had normal ultrasound findings. There were significant high LH and free testosterone levels in those
having PCOM group.
Conclusion: Significant differences were observed among free testosterone and LH levels between
Group-I having normal Ultrasound and Group-II PCOM. In addition to this, there is a significant
association of LH and testosterone with ultrasound findings which play a role in the early evaluation
of reproductive and metabolic status in adolescents.
Keyword: PCOS, Ultrasound, PCOM, LH, FSH Publication date: 01/04/2020 https://ijbpas.com/pdf/2020/April/MS_IJBPAS_2020_5009.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2020/9.4.5009