ABSTRACT

Methicillin Resistant Staphylococcus aureus (MRSA) are life threatening to the hospitalized patients and leads to endocarditis, skin and other wound infections especially in post operative surgical wounds. This study conducted to determine the prevalence and antibiotic susceptibility pattern of MRSA isolates in post-operative surgical wound infections from tertiary care hospital, Peshawar, Khyber Pakhtunkhwa province of Pakistan. A descriptive cross-sectional study was carried out in tertiary care hospitals Peshawar. Total of 3906 pus specimen were collected from nosocomial surgical wounded patients and antibiotic susceptibility pattern were determined through disc diffusion method in duration from January to September 2018. Out of total, S. aureus isolates were obtained from 827 (21.2%) samples. The overall proportions of Methicillin Resistant Staphylococcus aureus were 17.2% (n=142). Frequently infected patients were adults (83%) with high percentage of male (73.2%). For MRSA isolates, drug resistance was commonly observed while only few antibiotics (Vancomycin and Linezolid) were highly sensitive drug to MRSA. Moreover, Ciprofloxacin were least sensitive to Staphylococcus aureus isolates. MSSA isolates were sensitive nearly to all antimicrobial agents. This study determined the current prevalence of MRSA in surgical wounds along with the antibiotic susceptibility pattern of Staphylococcus aureus isolates from Peshawar. MRSA is associated with drug resistance, therefore imperative to monitor and control the spread of this lethal infection. Keywords: Antibiotics, MRSA, Post operative, Surgical Wounds
Publication date: 01/02/2020

https://ijbpas.com/pdf/2020/February/MS_IJBPAS_2020_4959.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.2.4959