ABSTRACT

Background: Intrauterine growth restriction (IUGR) is considered as serious complication relating to the female reproductive system. Condition if unattended may lead to the infertility in the group of patients. Primary aim of the current study is to compare the predictive accuracy in between trans-cerebellar diameter/abdominal circumference and head circumference/ abdominal circumference in patients with intrauterine growth restriction (IUGR). Methodology: For the present study two hundred (n=200) pregnant females with gestational age between 18-35 weeks and no other congenital anomaly and hundred (n=100) controls were substituted. Samples were obtained after getting informed consent at Bahria International Hospital Lahore-Pakistan. Ultrasonographic determination of BPD, FL, TCD, AC, HC and EFW were carried out and were then subjected to statistical analysis for the findings. Results: Results of the study suggest ratio of TCD/AC as the most accurate and significant measure in the early determination of gestational age and IUGR in patients. ROC curve findings also suggest maximum area under curve (AUC) such as, (0.911) in case of TCD/AC as compared to HC/AC where it restricts to (0.652). Furthermore, specificity and sensitivity in TCD/AC remains to (88%, 69%) respectively which is greater than that to compared with all other gynecological measures performed. Findings show that the best cut-off value of TCD/AC ratio is 14.3%. Conclusion: On the basis of findings of all the analytical and gynaelogical measures performed it concludes ratioof TCD/AC performed over the pregnant females was most accurate compared to HC/AC, BPD, EFW etc. Thus, the findings help to state that the said ratio is far more helpful in the determination of IUGR in early trimesters of pregnancies. Keywords: Intrauterine growth restriction (IUGR), Trans-cerebellar Diameter (TCD), Femur Length (FL), Biparietal Diameter (BPD)
Publication date: 01/02/2020

https://ijbpas.com/pdf/2020/February/MS_IJBPAS_2020_4949.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.2.4949