ABSTRACT

Present investigation includes evaluation of free radical scavenging potential of Abelmoschus manihot (A. manihot) (L.) Medik (Malvaceae), an important traditional medicinal herb in the Indian system of medicine. The dried powdered material of A. manihot flowers macerated to prepare total methanolic extract and solvent extraction technique prepared various fractions such as n-hexane fraction, ethyl acetate fraction and acetone fraction. Experimental design to screen extract and various fractions for its free radical scavenging potential by determining Nitric oxide (NO) radical, Superoxide (SO) radical, Hydrogen peroxide (OH) radical scavenging and anti-lipid peroxidation activity. Ascorbic acid was used as a standard drug. The results were revealed that A. manihot flowers have significant antioxidant potential when compared with standard. Our finding suggested that, the ethyl acetate fraction of A. manihot flowers having better efficacy and significant antioxidant activity. This work enlightens the antioxidant potential of this plant and also helps to support the traditional medicinal claim and believes of this plant in therapeutics. Keywords: Abelmoschus manihot, Malvaceae, Jangli bhendi, Free radicals, antioxidant effect
Publication date: 01/02/2020

https://ijbpas.com/pdf/2020/February/MS_IJBPAS_2020_4937.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.2.4937