EFFECT OF ETHANOLIC LEAVES EXTRACT OF Piper nigrum & Piper betle ON MULTI-DRUG RESISTANT MICROORGANISMS THAT AFFECT THE DIABETIC PATIENTS Authors: KAVITHA S , RAMESHKANNAN MV, MANI P
ABSTRACT
In Indian conventional medicine system, Piper nigrum and Piper betle are the
commonly used medicinal plants for various therapeutic purposes such as treatment of
antiulcer, antibacterial, antioxidant, anticancer etc., Diabetics mellitus is a disorder that
occurs due to the improper functioning of pancreas in secreting insulin that leads to increase
in blood glucose level which leads to various symptoms like frequent urination, loss of
weight, obesity, damage to the cells, dizziness, low blood pressure and very frequent
infection by pathogens such as Escherchia coli, Staphylococcus mutans, Klebseilla
pneumonia, Bacillus subtilis , Pseudomonas aeruginosa and Candida albicans. In the present
study aims to qualitative analysis the secondary metabolites from the ethanolic leaves extract
of Piper nigrum and Piper betle and testing the ethanolic leaves extract against multidrug
resistant microorganisms of diabetic foot ulcer. The results showed that the ethanolic leaves
extract of Piper nigrum and Piper betle exhibited the effective antibacterial activity against
the multidrug resistance organisms that affects the diabetic patients.
Keywords: Piper nigrum, Piper betle, Antibacterial Activity, Ethanolic extract and
Phytochemical analysis Publication date: 01/01/2020 https://ijbpas.com/pdf/2020/January/MS_IJBPAS_2019_4894.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2020/9.1.4894