ABSTRACT

Background: Chronic kidney disease (CKD), represent a diagnostic challenge. On the other hand, diabetes mellitus became a worldwide problem and also is considered as the main risk factor for Kidney Disease. Objectives: The aim of our study was to evaluate the prevalence of CKD among Sudanese patients and its association with diabetes mellitus. Methods: The study was carried out at Khartoum State, Sudan during the period of July 2017 to August 2017. Three hundred and seventy-five (375) CKD patients aged 18–90; their GFR was estimated using plasma creatinine and calculating kidney function by the Modification of Diet in Renal Disease (MDRD) equation. Patients with an estimated glomerular filtration rate (eGFR) less than 60 mL/min/1.73 m2 were considered as having CKD. Plasma creatinine, glucose, and medical history for presence of diabetes were also assessed. Results: The mean age of the subjects was 51.7 ± 14.4 SD and the prevalence of CKD for the overall percentage was 71 % with CKD and 29% without CKD. Moreover, we have found a high prevalence of CKD in diabetic patients within the male 76.8 % in comparison with female 75%groups. Regarding the association of diabetes mellitus with age in general, a higher prevalence of diabetes mellitus in younger was 86.5 % in female compared with 66.1 % in male was observed across age categories. Conclusion: This study showed that chronic kidney disease is widespread in Sudanese patients and is associated with younger and diabetic patients. Further studies should be undertaken to determine why the prevalence of diabetic nephropathy among Sudanese patients in these high-level levels. Keywords: Chronic Kidney Disease, Diabetes Mellitus, Diabetic Nephropathy, Risk Factors

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https://doi.org/10.31032/IJBPAS/2019/8.12.4801