DIAGNOSTIC ACCURACY OF PLEURAL FLUID CHOLESTEROL IN DIAGNOSIS OF EXUDATIVE PLEURAL EFFUSION
Authors: SARWER MI , TARIQ N2, FAROOQ U3, ZAFAR S4, AHMAD S4 AND MALIK A1*

ABSTRACT
Pleural effusion (PE) is defined as the abnormality that is characterized as the accumulation of fluid in the pleural space that results from collective factors i.e., excess fluid production or decreased absorption. The Light’s criteria serve as a good starting point in the separation of transudates from exudates. Pleural fluid cholesterol (PFC) is a useful parameter in ruling out the differences in between pleural exudates and transudates and exudates. 100 patients aging from 30-80 years were recruited in current study. Using 5cc BD syringe venous blood was drawn by staff nurse for the examination of protein, LDH and cholesterol. Data was analyzed using SPSS version 17. Reports for PFC and for Light’s criteria were assessed and EPF was labeled “positive” or “negative”. A 2x2 table was generated for the calculation of sensitivity, specificity, PPV, NPV and also to find out the diagnostic accuracy of the PFC which was taking as light’s criteria. Patients mean age was 55.78±13.53 years including 65% males and 35% females. Current study concludes that the determination of pleural effusion with the help of light’s criteria is less expensive and more accurate method. It also signifies the importance of cholesterol as a parameter for the determination of disorder with higher specificity and sensitivity. Keywords: Light’s criteria, Pleural Cholesterol, Exudative, Pleural Effusion, Estimation, Accuracy

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https://doi.org/10.31032/IJBPAS/2019/8.11.4861