ABSTRACT

Hepatitis B and C virus is invasive communicable disease of humans. That’s why there is a need to find out the existence and severity of the problem along its associated risk factors in urban area of Southern Punjab Multan Pakistan. Blood samples from1087 subjects were taken who came to donate blood in pathology lab. Data was taken with the help of a comprehensive questionnaire. Blood samples were tested with latest standard techniques i.e. immune chromatographic (ICT), enzyme linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR). The data was analyzed by chi square test and Statistical Package for Social Sciences (SPSS-21).Overall prevalence of HCV and HBsAg was 24.29% and 6.62% respectively. The liable epidemiological risk factors considered in HCV positive subjects were age, gender, economic status, family history, injection therapy, visit to barber/salon, ear/nose piercing, hospitalization, surgery/dental surgery, blood transfusion, illiteracy or low education, marital status and diabetes respectively, (P> 0.05).Obtained data showed higher prevalence of HCV and reasonably high frequency of HBV, whereas the probable epidemiological risk factors considered in HCV positive subjects were statistically not significant (P> 0.05). The higher prevalence of hepatitis virus might be due to low auto-immune response of the subjects. Keywords: Hepatitis B and C virus, Immune chromatographic, Enzyme linked immunosorbent assay, Polymerase chain reaction, auto-immune response

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https://doi.org/10.31032/IJBPAS/2019/8.11.4854