Lantana camara is one of the medicinal plants of verbenacea family, used extensively in herbal
medicine to treat several diseases. The present study was carried out to determine the possible
phytochemical components present in ethyl acetate fraction of Lantana camara leaves and
evaluate the bioactive compounds using Gas Chromatograph-Mass spectrometry. Gas
chromatography-mass spectroscopy was used to carry out analysis. Mass spectra of the unknown
compounds found in the fraction were matched with standard mass spectra of known
components stored in National Institute of Standards and Technology (NIST) library. Result: GC
MS analysis produced 19 peaks, corresponding to constituent compounds present in the sample.
The eight major phytoconstituents identified were 2,2,4-trimethyl-3-(3,8,12,16-tetramethylheptadeca-
3,7,11,15-tetraenyl)-cyclohexanol, 9,12,15 octadecatrienoic acid, 2, 3-
dihydroxypropyl ester, phytol, aromadendrene oxide(-2) and its isomer, spathulenol, 3,7,11,15-
tetramethyl-2-hexadecen-1-ol, 6- epi-shyobunol, hexadecanoic acid, and 1-(hydroxymethyl)-1,2-
ethanediyl ester. These major compounds add up to 80.15 % of total constituents. Minor
constituents identified were caryophyllene, ledene oxide-(II), cycloheptasiloxane
tetradecamethyl, propanoic acid,2-[3-acetoxy-4,4,14-trimethylandrost-8-en-17yl], 1,6,10-
dodecatrien-3-ol,3,7,11-trimethyl-[s-(z)], humulene, 13-heptadecyn-1-ol, ?- acorenol, ergosta-5,22-dien-3-ol, acetate, [3?, 22E] and 1-heptatriacotanol, all summing up to 19.84 % of total
constituents. The presence of various bioactive compounds identified in ethyl acetate fraction of
Lantana camara leaves, justifies the use of the plant for diverse ailments by traditional
practitioners and can be proposed as a plant of phyto-pharmaceutical relevance.
Keywords: Bioactive compounds, GC MS, Lantana camara, medicinal properties
https://ijbpas.com/pdf/2019/November/MS_IJBPAS_2019_4819.pdf
Download PDF
https://doi.org/10.31032/IJBPAS/2019/8.10.4819
