RNA INTERFERENCE: APPLICATIONS AND CONFRONTATIONS Authors: WAEL ABU DAYYIH , MOHAMED JAMAL SAADH1, HALA MOUSA SBAIH2, HUSSIEN M. ABUKTAISH2, QUTAIBA AHAMD AL KHAMES AGA2, ZAINAB ZAKAREIA3
ABSTRACT
Ribonucleic acid interference (RNAi) is one of modern techniques which involved in
suppressing protein productions , this occurred via inserted of double stranded (ds) RNA into the
cytoplasm in a cell which leads to particulate and effective degradation of complementary
messenger (m RNA).
It discovered fortuitously during attempts to produce flowers with elevated color intensity. The
possible of this technique to recognizing the physiological and pathological processes is vet
important, while its improvement as a therapeutic agent carries out much promise as targeted
therapeutic agents.
This review article will discuss the basic biological processes that drive RNAi, indicate present
and prediction future areas research, and some of applicable limitations.
Keywords: Ribonucleic acid, interference, (RNAi), m RNA