Global and Indian scenario of cancer is devastating with 23.6 million new cases to be reported
each year till 2030. According to world cancer report of 2014, the cancer death is known to have
risen from 8.2 million to 13 million per year. According to World Cancer Report 2014, Africa,
Asia, and Central and South America are the most predominant regions accounting for 60% of
the worldwide cancer cases and 70% of the total deaths caused by cancer worldwide. It is
reported that the prevalence of cancer is more in males as compared to females giving a ratio of
10:9. On considering Indian scenario, India alone contributes to 7.8% of the world cancer
burden accounting for 1.1 million new cases of cancer. Approximately one billion of total world
population is comprised of Asian Indians of which 20 million population lives outside India.
With the increasing incidence of cancer, it has now become a recent area of therapeutics and theclinical advancement in the cure of cancer is incredible. Although the success of these drugs and
therapies are inevitable but still various side effects has been incurred such as skin toxicity,
gastrointestinal toxicity, cardiovascular toxicity, bone marrow depression, alopecia, surface
epithelial damage, kidney damage, dysphagia, cardiotoxicity, peripheral neuropathy etc. Besides
curing the disease, anticancerous drugs also possess toxicity that contributes to higher death rates
among cancer bearing patients and specially chemotherapy are associated with wide range of
severe side effects. Other therapies like radiation therapy, molecular targeted therapy possess
severe side effects that are inevitable. Sovarious strategies and treatment therapies for complete
cure of cancer are under seen like use of gamma knife, cyber knife, radioactive iodine seeds and
currently a new strategy to targeting angiogenesis by inhibiting VEGFR, EGFR and other
tyrosine kinase inhibitors like Sunitinib, Sorafenib, Pazopanib are currently in use. Besides use
of drugs, a novel instrument known as TexRAD is used to analyze texture of the given sample
and the data produced via using computer application are further processed for disease
identification.
Keywords: Cancer, Global scenario, Indian scenario, anticancer drugs, side effects, recent development
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https://doi.org/10.31032/IJBPAS/2019/8.9.4807
