ABSTRACT

Objective: To investigate the influences of age, sex, body mass index (BMI), the Kellgren Lawrence radiological osteoarthritis index (KLOAI) on the severity and functional disability of patients with primary knee osteoarthritis (PKO). Methods: 70 patients, 60 females, 10 males from our outpatient clinic diagnosed as PKO according to American College of Rheumatology were involved in the study. Bilateral standing AP knee radiography of all patients were taken and evaluated according to the KLOAI. BMI was calculated as the weight in Kg divided by the square of the height in meters. Lequesne index (LI), painless walking distance (PWD), painless walking duration (PWD,) were used to estimate the severity and functional disability of PKO. Results: After controlling for age, gender and BMI, for each unit increase in KLOAI the LI is expected to increase by a mean of 1.5 units. Males had a significantly lower mean LI (by 3.8 units) compared to females of similar age, BMI and radiological severity. Older age was associated with a more severe LI, for each year increase in age the LI is expected to increase by 0.1 unit when controlling for radiological severity, gender and BMI. There was significant correlation between BMI and radiological severity. Conclusion: Obesity as measured by BMI was associated with definite knee OA. Radiographic changes as measured by KLOAI had significant correlation with severity of PKO as measured by LI. Patients with older age had more severe PKO. Males have lower severity of PKO than females. LI can be used in daily practice to follow up the OA in weight bearing joints. Keywords: knee, osteoarthritis, disability, radiological severity

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https://doi.org/10.31032/IJBPAS/2019/8.9.4792