ABSTRACT

Paracetamol is mostly prescribed and OTC drug. Paracetamol is normally used to get moderate pain reliever. It is similarly used as antipyretic in kids and can be used in combination with other medication to treat cold. Paracetamol is also used in different diseases related to headache and headache caused by stress. Good manufacturing practice (GMP) is part of quality assurance department in which products are manufactured according to the standard. Quality confirmation is the substance of value control. QA may likewise characterize as all exercises acknowledged going before and counteracting low quality. This study was comprised to analyse the Quality check of different brands of Paracetamol. Seven different brands of Paracetamol were collected from the market of Quetta city, Pakistan to analyse the physiochemical properties, these results were compared with each other and with standards. The physiochemical tests were performed they were Weight variation, Hardness, Thickness, Friability, Disintegration and Dissolution. The results were analysed and compared with standards. Different brands of Paracetamol were checked their physiochemical properties and showed slight difference in their physiochemical analysis but found within acceptable range. All the results showed within the acceptable range which indicates that the pharmaceutical companies are following the standard specifications. Keywords: Paracetamol, Physiochemical Properties, Quetta

https://ijbpas.com/pdf/2019/August/MS_IJBPAS_2019_4793.pdf

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https://doi.org/10.31032/IJBPAS/2019/8.8.4793