ABSTRACT

This research investigation has been designed to synthesize novel clove oil coated natural hydroxyapatite composite particles using residual bones. The bone waste was consumed for extraction of natural bone precursor hydroxyapatite. This work was executed to investigate the benefits of using essential clove oil coated hydroxyapatite composite in dentistry, especially for its preventive, restorative and regenerative applications. The clove oil coated natural hydroxyapatite composite particles were characterized using standard physicochemical characterization viz. XRD, SEM, FTIR, TEM and EDX. The thermal stability of clove oil coated natural hydroxyapatite composite particles was ascertained by TGA-DTA analysis. Moreover, the clove oil coated natural hydroxyapatite composite particles were tested for the antimicrobial activities using preferred Gram positive (S. aureus ATCC 29213 and S. epidermidis ATCC 12228) and Gram negative (E. coli ATCC 35218 and K. pneumoniae ATCC 700603) bacteria. The antifungal activity was tested using C. albicans ATCC 10231 as model organism. The clove oil functionalized hydroxyapatite composite particles material depicted broad spectrum antimicrobial potential which strongly recommends their use as material of choice for potentialdental implants. Keywords: Cow bones, Hydroxyapatite, Clove oil, Composite, antimicrobial, antifungal

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https://doi.org/10.31032/IJBPAS/2019/8.5.4717