PHARMACOLOGICAL AND PHYTOCHEMICAL STUDIES OF ETHANOLIC EXTRACT OF ZIZIPHUS OXYPHYLLA ROOT Authors: SHAIRBAZ KHAN1 , SHAFI MUHAMMAD1, ABDUL JABBAR1, TAUFIQUE AHMAD2, AMJAD HUSSAIN2 AND SULTAN AYAZ3
ABSTRACT
Ziziphus oxyphylla is locally known as gargola. It is found in district Barkhan, Balochistan.
Current study involves phytochemical, neuropharmacological evaluation of root of Z. oxyphylla.
In Phytochemical investigation alkaloids, flavanoids, glycosides, saponins, steroids and tannins
were present. At 250 and 500 mg/kg oral doses of crude extract showed significant (p<0.05)
analgesic effects. In neuropharmacological activites plant showed significant CNS depressant
activity. These Pharmacological activities confirm the traditional claim of the plant.
Keywords: Phytochemical, Neuropharmacological evaluation, Ziziphus oxyphylla