ABSTRACT

Background: Viral hepatitis places a heavy burden on the health care. Large number of patient with bleeding disorders has chronic hepatitis C infection, while few are chronic carriers of hepatitis B virus. Aims of study: evaluate the prevalence of HBV, HCV infection among patient with Von Willebrand disease and to find factors that associated with the chance of getting the infection. Materials and methods: A cross sectional study was conducted on 145 patients with von Willebrand disease who registered in Hereditary Bleeding Disorders Unit at Medical City, Baghdad, during period between first of December 2017 to the 31st of July 2018. SPSS version 24 was used in statistical analysis. Descriptive statistics were presented as frequency and percentages. Chi-square test for association. P ? 0.05 considered as a significant association. Results: Out of total 145 patients, 16 patients were HCV antibody positive with a prevalence of 11% , None of the patients had HBV. There is a significant statistical association between the patient age and hepatitis C viral infection, (20%) of patients ages between 20-29 years were seropositive to HCV. the majority of patient 33.3% showed Significant association between duration of disease and hepatitis C infection sero-positive (P? 0.05). Conclusion: The prevalence of hepatitis C was high. The prevalence of hepatitis C is statistically significantly related to increase age, duration of disease and number of cryoprecipitate transfusion. Keywords: prevalence, hepatitis infection, risk factors, von Willebrand’s disease, patients, Baghdad

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https://doi.org/10.31032/IJBPAS/2019/8.2.4615