ABSTRACT

The functional biological activities of leaf extracts of Morus sp. S54 variety were investigated in this study. The antifungal, antioxidant, total phenolic content and the teratogenic effect of the plant extracts were evaluated. Both ethanol and water extract showed antifungal activity against Aspergillus niger with diameter zones of inhibition of 19.24 mm and 17.60 mm, respectively. Extract of Morus leaf also exhibited DPPH radical scavenging activity with a mean of 12.93% and contained a total phenolic content of 67 mgAAE/g of sample. In teratogenicity assay, coagulation was the most toxic effect observed in higher concentrations of water extract. Tail malformation and growth retardation were the most common teratogenic effects observed in developing Danio rerio embryos. Keywords: Antifungal, antioxidant, total phenolic content, teratogenic effect, Morus sp. S54 variety

https://ijbpas.com/pdf/2018/March/1519987627MS IJBPAS 2018 4401.pdf

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